Instance ID11128
Regular Expressionxxx([ST])Px
Motif InstanceVGHSPE
Bait Uniprot AccessionQ8CFN5
Bait Uniprot IdentifierMEF2C_MOUSE
Bait Gene NameMef2c
Bait OrganismMus musculus (Mouse)
Sequence Position107-112
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Phosphatase assay; Mutation analysis; Western blot; Co-IP; Alanine scanning; Pull down
Interaction ID21128
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20801874
CommentsMouse Peptidyl-prolyl cis-trans isomerase Pin1 interacts selectively with the phosphorylated Ser-110-Pro motif of mouse Myocyte-specific enhancer factor 2C (Mef2c) in skeletal muscle cells and acts as a regulator of muscle terminal differentiation

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)