Instance ID11130
Regular Expressionxxx([ST])Px
Motif InstanceQEISPP
Bait Uniprot AccessionQ05397
Bait Uniprot IdentifierFAK1_HUMAN
Bait Gene NamePTK2
Bait OrganismHomo sapiens (Human)
Sequence Position907-912
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Classical fluorescence spectroscopy; Western blot; Pull down; Mutation analysis
Interaction ID21130
Interacting DomainWW domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)19595712
CommentsThe human Peptidyl-prolyl cis-trans isomerase PIN1 interacts with the Ser-910-Pro motif of human Focal adhesion kinase 1 (FAK1) and may thereby play a role in Ras-related tumor metastasis

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)