Instance ID11133
Regular Expressionxxx([ST])Px
Motif InstanceGPQSPG
Bait Uniprot AccessionP14598
Bait Uniprot IdentifierNCF1_HUMAN
Bait Gene NameNCF1
Bait OrganismHomo sapiens (Human)
Sequence Position342-347
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Far Western blotting; Pull down
Interaction ID21133
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20956805
CommentsThe human Peptidyl-prolyl cis-trans isomerase PIN1 binds to human Neutrophil cytosol factor 1 (NCF1)/p47phox on phosphorylated Ser345, thereby inducing conformational changes that facilitate p47phox phosphorylation on other sites by protein kinase C

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)