Instance ID11137
Regular Expressionxxx([ST])Px
Motif InstanceNPFTPD
Bait Uniprot AccessionQ8QGV2
Bait Uniprot IdentifierWEE1B_XENLA
Bait Gene Namewee1-b
Bait OrganismXenopus laevis (African clawed frog)
Sequence Position183-188
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Thr-P4
Secondary StructureUnknown
Experimental Method(s)Western blot; Pull down; Alanine scanning
Interaction ID21137
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17360425
CommentsProlyl isomerase Pin1 from Xenopus laevis specifically binds the phosphorylated Thr-186-Pro motif of Xenopus Zygotic wee1-like protein kinase 1B, the inhibitory kinase of cyclin B/Cdc2, for its catalytic inactivation at M phase of the mitotic cell cycle

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)