Instance ID11144
Regular Expressionxxx([ST])Px
Motif InstanceAYLSPP
Bait Uniprot AccessionQ3U182
Bait Uniprot IdentifierCRTC2_MOUSE
Bait Gene NameCrtc2
Bait OrganismMus musculus (Mouse)
Sequence Position133-138
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Pull down; Co-IP; Alanine scanning
Interaction ID21144
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20675384
CommentsMouse Peptidyl-prolyl cis-trans isomerase Pin1 associates with and induces translocation of mouse CREB-regulated transcription coactivator 2 (Crtc2) to the cytosol, thereby suppressing cAMP-responsive element transcriptional activity

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)