Instance ID11146
Regular Expressionxxx([ST])Px
Motif InstanceGRSSPS
Bait Uniprot AccessionP78543
Bait Uniprot IdentifierBTG2_HUMAN
Bait Gene NameBTG2
Bait OrganismHomo sapiens (Human)
Sequence Position144-149
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Co-IP; Pull down; Mutation analysis
Interaction ID21146
Interacting DomainWW domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)15788397
CommentsPhosphorylation of serine 147 of human NGF-inducible anti-proliferative protein PC3/BTG2 induces binding to human Peptidyl-prolyl cis-trans isomerase PIN1 in cytoplasm and cell death

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)