Instance ID11147
Regular Expressionxxx([ST])Px
Motif InstanceAAVTPE
Bait Uniprot AccessionP05067
Bait Uniprot IdentifierA4_HUMAN
Bait Gene NameAPP
Bait OrganismHomo sapiens (Human)
Sequence Position740-745
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Thr-P4
Secondary StructureUnknown
Experimental Method(s)Western blot
Interaction ID21147
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19602287
CommentsThe human Peptidyl-prolyl cis-trans isomerase PIN1 binds human Amyloid beta A4 protein (APP) phosphorylated on Thr-743 and regulates APP processing

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)