Instance ID11148
Regular Expressionxxx([ST])Px
Motif InstanceQEISPP
Bait Uniprot AccessionP34152
Bait Uniprot IdentifierFAK1_MOUSE
Bait Gene NamePtk2
Bait OrganismMus musculus (Mouse)
Sequence Position907-912
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Protein kinase assay; Pull down; Classical fluorescence spectroscopy; Mutation analysis; Western blot
Interaction ID21148
Interacting DomainWW domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)19595712
CommentsMouse Peptidyl-prolyl cis-trans isomerase Pin1 interacts with the Ser-910-Pro motif of mouse Focal adhesion kinase 1 (Fak1/Ptk2) and may thereby play a role in Ras-related tumor metastasis

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)