Instance ID11150
Regular Expressionxxx([ST])Px
Motif InstanceEPASPP
Bait Uniprot AccessionP37231
Bait Uniprot IdentifierPPARG_HUMAN
Bait Gene NamePPARG
Bait OrganismHomo sapiens (Human)
Sequence Position81-86
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Western blot; SPR; Pull down; Mutation analysis; Co-IP
Interaction ID21150
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19996102
CommentsThe WW domain of human Peptidyl-prolyl cis-trans isomerase PIN1 interacts with the phosphorylated Ser-84-Pro motif of human Peroxisome proliferator-activated receptor gamma (PPARG) and thereby regulates macrophage function

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)