Instance ID11155
Regular Expressionxxx([ST])Px
Motif InstanceVVRTPP
Bait Uniprot AccessionP10636
Bait Uniprot IdentifierTAU_HUMAN
Bait Gene NameMAPT
Bait OrganismHomo sapiens (Human)
Sequence Position228-233
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Thr-P4
Secondary StructureUnknown
Experimental Method(s)ELISA; Alanine scanning; Pull down
Interaction ID21155
Interacting DomainWW domain
Disease Association(s)Alzheimer's disease
Inhibitor(s)Unknown
Reference(s)10391244
CommentsThe human Peptidyl-prolyl cis-trans isomerase PIN1 exhibits specific and high-affinity binding to the phosphorylated Thr-231-Pro motif of Isoform Tau-F (Tau-4) of human Microtubule-associated protein tau (MAPT)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)