Instance ID11164
Regular Expression[LV][DE][^P][LM][LM][^P][^P]L[^P]
Motif InstanceLDALLADLE
Bait Uniprot AccessionP49023
Bait Uniprot IdentifierPAXI_HUMAN
Bait Gene NamePXN
Bait OrganismHomo sapiens (Human)
Sequence Position4-12
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Co-IP; Peptide binding to perpetrator; Pull down(His tag); Pull down(GST tag); Competition binding; Mutation analysis; Colocalization
Interaction ID21164
Interacting DomainFAT domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20489202, 11304546, 10330411, 11134073
CommentsHuman Paxillin (PXN) interacts with human Focal adhesion kinase 1 (FAK1/PTK2) through its LD motif (4-12)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)