Instance ID11167
Regular Expressionxx(T)xx[ILV]x
Motif InstanceVETTSVF
Bait Uniprot AccessionP9WJA9
Bait Uniprot IdentifierGARA_MYCTU
Bait Gene NamegarA
Bait OrganismMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Sequence Position19-25
Critical ResiduesP3
Motif PTM(s)Phosphorylation at Thr-P3
Secondary StructureUnknown
Experimental Method(s)NMR; ITC
Interaction ID21167
Interacting DomainFHA domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19318624
CommentsPhosphorylation of a threonine residue within a conserved amino-terminal motif of Glycogen accumulation regulator garA/Rv1827 triggers its intramolecular association with its FHA domain in Mycobacterium tuberculosis

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)