Instance ID11171
Regular Expressionxx(T)xx[DE]x
Motif InstanceGSTDEES
Bait Uniprot AccessionQ924T3
Bait Uniprot IdentifierXRCC4_MOUSE
Bait Gene NameXrcc4
Bait OrganismMus musculus (Mouse)
Sequence Position229-235
Critical ResiduesP3
Motif PTM(s)Phosphorylation at Thr-P3
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography
Interaction ID21171
Interacting DomainFHA domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15749016
CommentsMouse Bifunctional polynucleotide phosphatase/kinase Pnkp is recruited to repair complexes through interactions between its N-terminal FHA domain and a phosphorylated threonine residue (T231) in mouse DNA repair protein Xrcc4

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)