Instance ID11174
Regular Expressionxx(T)xx[DE]x
Motif InstanceENTDSEE
Bait Uniprot AccessionP18887
Bait Uniprot IdentifierXRCC1_HUMAN
Bait Gene NameXRCC1
Bait OrganismHomo sapiens (Human)
Sequence Position521-527
Critical ResiduesP3
Motif PTM(s)Phosphorylation at Thr-P3
Secondary StructureUnknown
Experimental Method(s)Fluorescence polarization spectroscopy; Mutation analysis
Interaction ID21174
Interacting DomainFHA domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15367657
CommentsThe FHA domain of human Bifunctional polynucleotide phosphatase/kinase PNKP binds to a phosphothreonine motif (T523) from human DNA repair protein XRCC1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)