Instance ID11175
Regular Expression[EN][FYLW][NSQ]xEE[ILMVF][^P][LIVMFA]
Motif InstanceEFSLEEVLA
Bait Uniprot AccessionP47074
Bait Uniprot IdentifierMAD3_YEAST
Bait Gene NameMAD3
Bait OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence Position378-386
Critical ResiduesP1; P5
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)X-ray crystallography; Pull down; Co-IP; Y2H; Mutation analysis
Interaction ID21175
Interacting DomainWD40 repeat domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17227844
CommentsThe Gle2-binding-sequence (GLEBS) motif found in yeast Spindle assembly checkpoint component MAD3 protein binds to the WD40 domain of yeast Cell cycle arrest protein BUB3

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)