Instance ID11180
Regular Expression[QHR]x{0,1}P[PL]PP[GS]H[RH]
Motif InstanceHRPPPPGHR
Bait Uniprot AccessionP06729
Bait Uniprot IdentifierCD2_HUMAN
Bait Gene NameCD2
Bait OrganismHomo sapiens (Human)
Sequence Position295-303
Critical ResiduesP7; P8; P9
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)Y2H; NMR; Mutation analysis
Interaction ID21180
Interacting DomainGYF domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12426371
CommentsThe GYF domain of the human CD2 antigen cytoplasmic tail-binding protein 2 (CD2BP2) binds to a proline-rich sequence (295-303) in the cytoplasmic tail of human T-cell surface antigen CD2

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)