Instance ID11184
Regular ExpressionL[^P]{2,2}[HI]I[^P]{2,2}[IAV][IL]
Motif InstanceLEAIIRKAL
Bait Uniprot AccessionQ9Y618
Bait Uniprot IdentifierNCOR2_HUMAN
Bait Gene NameNCOR2
Bait OrganismHomo sapiens (Human)
Sequence Position2350-2358
Critical ResiduesP1; P5; P9
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)X-ray crystallography; Mutation analysis
Interaction ID21184
Interacting DomainAF-2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11845213
CommentsThe corepressor nuclear receptor (CORNR) box (2350-2358) found in the human Nuclear receptor corepressor 2 (NCOR2)/ SMRT that confers binding to the AF-2 domain of human Peroxisome proliferator-activated receptor alpha (PPARA)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)