Instance ID11197
Regular Expression[WFY]RP[WFY]x{0,7}$
Motif InstanceWRPWRN
Bait Uniprot AccessionQ14469
Bait Uniprot IdentifierHES1_HUMAN
Bait Gene NameHES1
Bait OrganismHomo sapiens (Human)
Sequence Position275-280
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Mutation analysis
Interaction ID21197
Interacting DomainWD domain, G-beta repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12972610
CommentsThe interaction of human Transcription factor HES-1 with the human transcriptional co-repressor Transducin-like enhancer protein 1 (TLE1) is mediated by a WRPW tetrapeptide motif in HES-1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)