Instance ID11202
Regular Expression[ED][ED][ED]x[IV]Yx
Motif InstanceEEENIYS
Bait Uniprot AccessionQ91YM2
Bait Uniprot IdentifierRHG35_MOUSE
Bait Gene NameArhgap35
Bait OrganismMus musculus (Mouse)
Sequence Position1100-1106
Critical ResiduesP2; P3; P5; P6
Motif PTM(s)Phosphorylation at Tyr-P6
Secondary StructureUnknown
Experimental Method(s)Site-directed Mutagenesis; In-vitro assay using fluorogenic peptide probes
Interaction ID21202
Interacting DomainCatalytic domain of Ptprz
Disease Association(s)Impaired hippocampus-dependent contextual fear mem
Inhibitor(s)Unknown
Reference(s)21890632
CommentsConsensus sequence for association with protein-tyrosine phosphatase receptor type zeta in mouse Rho GTPase-activating protein 35 (Arhgap35)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)