Instance ID11206
Regular ExpressionWxP
Motif InstanceWHP
Bait Uniprot AccessionF5H9D8
Bait Uniprot IdentifierF5H9D8_HHV8
Bait Gene NamevIRF-4
Bait OrganismHuman herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Sequence Position471-473
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Site-directed mutagenesis; Hybridization of peptide arrays; Y2H; Competition binding assay
Interaction ID21206
Interacting DomainBeta-trefoil domain
Disease Association(s)Kaposi's sarcoma
Inhibitor(s)Unknown
Reference(s)20861242
CommentsShort peptide motif in VIRF-4 protein of Human herpesvirus 8 through which it targets the hydrophobic pocket in the beta trefoil domain of CSL/CBF1 (RBPJ)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)