Instance ID11208
Regular ExpressionWxP
Motif InstanceWFP
Bait Uniprot AccessionQ01705
Bait Uniprot IdentifierNOTC1_MOUSE
Bait Gene NameNotch1
Bait OrganismMus musculus (Mouse)
Sequence Position1758-1760
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21208
Interacting DomainBeta-trefoil domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)8749394, 20028974
CommentsThe conserved WFP sequence motif within the RAM region of mouse Notch1 protein that mediates binding to the beta trefoil domain (or BTD) of mouse RBP-J kappa

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)