Instance ID11209
Regular ExpressionWxP
Motif InstanceWFP
Bait Uniprot AccessionQ61982
Bait Uniprot IdentifierNOTC3_MOUSE
Bait Gene NameNotch3
Bait OrganismMus musculus (Mouse)
Sequence Position1676-1678
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; Mutational analysis; ITC
Interaction ID21209
Interacting DomainBeta-trefoil domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)8898100, 20028974
CommentsThe conserved WFP sequence motif within the RAM region of mouse Notch3 protein that mediates binding to the beta trefoil domain (or BTD) of mouse RBP-J kappa

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)