Instance ID11210
Regular ExpressionWxP
Motif InstanceWLP
Bait Uniprot AccessionO35516
Bait Uniprot IdentifierNOTC2_MOUSE
Bait Gene NameNotch2
Bait OrganismMus musculus (Mouse)
Sequence Position1706-1708
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; Mutational analysis; ITC
Interaction ID21210
Interacting DomainBeta-trefoil domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)8898100, 20028974
CommentsThe conserved WFP sequence motif within the RAM region of mouse Notch2 protein that mediates binding to the beta trefoil domain (or BTD) of mouse RBP-J kappa

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)