Instance ID11211
Regular ExpressionWxP
Motif InstanceWLP
Bait Uniprot AccessionP31695
Bait Uniprot IdentifierNOTC4_MOUSE
Bait Gene NameNotch4
Bait OrganismMus musculus (Mouse)
Sequence Position1478-1480
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; Mutational analysis; ITC
Interaction ID21211
Interacting DomainBeta-trefoil domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)8898100, 20028974
CommentsThe conserved WFP sequence motif within the RAM region of mouse Notch4 protein that mediates binding to the beta trefoil domain (or BTD) of mouse RBP-J kappa

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)