Instance ID11218
Regular ExpressionPPPYx{4,4}[ST][ILV]
Motif InstancePPPYHADPSL
Bait Uniprot AccessionO15350
Bait Uniprot IdentifierP73_HUMAN
Bait Gene NameTP73
Bait OrganismHomo sapiens (Human)
Sequence Position484-493
Critical ResiduesP1; P2; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction
Interaction ID21218
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20855944
CommentsHuman E3 ubiquitin-protein ligase ITCH, a group I WW domain protein, and human Tumor protein TP73 interact with each other through the WW2 domain and the consensus PPxY or PY motif

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)