Instance ID11223
Regular ExpressionPPPYx{4,4}[ST][ILV]
Motif InstancePPPYRHRNTV
Bait Uniprot AccessionQ15303
Bait Uniprot IdentifierERBB4_HUMAN
Bait Gene NameERBB4
Bait OrganismHomo sapiens (Human)
Sequence Position1298-1307
Critical ResiduesP1; P2; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction
Interaction ID21223
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20855944
CommentsHuman E3 ubiquitin-protein ligase ITCH, a group I WW domain protein, and human Proto-oncogene-like protein c-ErbB-4 (ERBB4) may interact with each other through the WW2 domain and the consensus PPxY or PY motif

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)