Instance ID11228
Regular Expression[ST]x[VL]D
Motif InstanceSSVD
Bait Uniprot AccessionQ9NQC7
Bait Uniprot IdentifierCYLD_HUMAN
Bait Gene NameCYLD
Bait OrganismHomo sapiens (Human)
Sequence Position361-364
Critical ResiduesP3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction
Interaction ID21228
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)22876914
CommentsNovel internal motif identified in human Ubiquitin carboxyl-terminal hydrolase CYLD that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)