Instance ID11237
Regular ExpressionxGxxPG
Motif InstancePGAIPG
Bait Uniprot AccessionP15502
Bait Uniprot IdentifierELN_HUMAN
Bait Gene NameELN
Bait OrganismHomo sapiens (Human)
Sequence Position286-291
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)Sequence based prediction; Chemotaxis assay; Gelatin zymography; ELISA
Interaction ID21237
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Emphysema; Aneurysm; Cancer
Inhibitor(s)Galactosugars
Reference(s)8388074, 8396888, 15148686, 11084020, 1848864, 8034752, 2550450, 11723829
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a chemokinetic hexapeptide (286-291) from human Tropoelastin and mediates cell adhesion to elastin and elastin fiber assembly


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)