Instance ID11238
Regular ExpressionxGxxPG
Motif InstanceVGVAPG
Bait Uniprot AccessionP15502
Bait Uniprot IdentifierELN_HUMAN
Bait Gene NameELN
Bait OrganismHomo sapiens (Human)
Sequence Position506-511
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)NMR; CD; Fluorimetric measurements
Interaction ID21238
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Emphysema; Aneurysm; Cancer
Inhibitor(s)Galactosugars
Reference(s)15148686, 19241470, 23166321, 1848864, 8034752, 2550450
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a chemokinetic hexapeptide (506-511) from human Tropoelastin and mediates cell adhesion to elastin and elastin fiber assembly

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)