Instance ID11243
Regular ExpressionxGxxPG
Motif InstanceEGFEPG
Bait Uniprot AccessionP35555
Bait Uniprot IdentifierFBN1_HUMAN
Bait Gene NameFBN1
Bait OrganismHomo sapiens (Human)
Sequence Position2194-2199
Critical ResiduesP5
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)Site-directed Mutagenesis; Chemotaxis assay
Interaction ID21243
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Marfan syndrome
Inhibitor(s)Unknown
Reference(s)16442122, 17030689
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a hexapeptide motif from human Fibrillin-1 (FBN1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)