Instance ID11259
Regular Expression[KR]xTQTx
Motif InstanceKSTQTP
Bait Uniprot AccessionO43521
Bait Uniprot IdentifierB2L11_HUMAN
Bait Gene NameBCL2L11
Bait OrganismHomo sapiens (Human)
Sequence Position111-117
Critical ResiduesP3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)NMR; Mutational analysis; Y2H
Interaction ID21259
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10198631, 11178896, 14561217
CommentsThe proapoptotic activity of the human Bcl-2 family member BIM (BCL2L11) is regulated by interaction with the 8 kDa Dynein light chain 1 (DYNLL1/DLC8) through a conserved (K/R)XTQT consensus sequence

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)