Instance ID11290
Regular Expression[DS]Kx[TVI]Q[TV][DE]
Motif InstanceSAATQTI
Bait Uniprot AccessionQ12888
Bait Uniprot IdentifierTP53B_HUMAN
Bait Gene NameTP53BP1
Bait OrganismHomo sapiens (Human)
Sequence Position1168-1174
Critical ResiduesP4; P5; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)NMR; Mutational analysis
Interaction ID21290
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15611139, 21533121
CommentsThe LC8 dynein light chain binding motif (1168-1174) in human Tumor suppressor p53-binding protein 1 (TP53BP1) that binds to the human 8 kDa Dynein light chain 1 (DYNLL1/DLC8) and mediates DNA damage-induced p53 nuclear accumulation

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)