Instance ID11348
Regular ExpressionRPVAxVxPxxR
Motif InstanceRPVAMVIPARR
Bait Uniprot AccessionQ9QXS1
Bait Uniprot IdentifierPLEC_MOUSE
Bait Gene NamePlec
Bait OrganismMus musculus (Mouse)
Sequence Position102-112
Critical ResiduesP6; P8
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; Peptide binding assay; SPR
Interaction ID21348
Interacting DomainSubstrate-binding domain(SBD) of SINA/Siah proteins
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12626763
CommentsDegradation signal or “degron” motif in mouse plectin-1 which mediates binding to the Siah2 ubiquitin ligase

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)