Instance ID11424
Regular ExpressionLxxLL
Motif InstanceLHRLL
Bait Uniprot AccessionQ61026
Bait Uniprot IdentifierNCOA2_MOUSE
Bait Gene NameNcoa2
Bait OrganismMus musculus (Mouse)
Sequence Position690-694
Critical ResiduesP4; P5
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Y2H; Mutational analysis
Interaction ID21424
Interacting DomainAF-2 transcriptional activation domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9482670
CommentsCore LXXLL motif sequence (NR Box II) in NCOA2 required for the ligand-dependent binding to the Glucocorticoid receptor

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)