Instance ID11465
Regular ExpressionWxxLF
Motif InstanceWHTLF
Bait Uniprot AccessionP10275
Bait Uniprot IdentifierANDR_HUMAN
Bait Gene NameAR
Bait OrganismHomo sapiens (Human)
Sequence Position433-437
Critical ResiduesP1; P4; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Mammalian two-hybrid assay; GST interaction assay
Interaction ID21465
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10816582
CommentsThe WXXLF sequence in the N-terminal domain of Androgen receptor(AR), a second androgen-independent interaction site, that probably interacts with a region of the LBD outside of AF2 and mediates a direct interaction between the N-terminal and C-terminal regions of AR

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)