Instance ID11513
Regular Expression[ST]x[VL]$
Motif InstanceTLV
Bait Uniprot AccessionP89079
Bait Uniprot IdentifierE4OR1_ADE09
Bait Gene NameE4
Bait OrganismHuman adenovirus D serotype 9 (HAdV-9) (Human adenovirus 9)
Sequence Position123-125
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutational analysis; Pull down(GST tag)
Interaction ID21513
Interacting DomainPDZ domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)9192623
CommentsC-terminal PDZ domain-binding motif in the Ad9 E4-ORF1 oncoprotein that mediates its binding to hDLG/SAP97, the mammalian homolog for the Drosophila discs large tumor suppressor protein Dlg-A

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)