Instance ID11525
Regular Expression[ST]x[VL]$
Motif InstanceTQV
Bait Uniprot AccessionP06463
Bait Uniprot IdentifierVE6_HPV18
Bait Gene NameE6
Bait OrganismHuman papillomavirus type 18
Sequence Position156-158
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutational analysis; Pull down(GST tag)
Interaction ID21525
Interacting DomainPDZ domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)11000240
CommentsPDZ domain-binding motif in E6 oncoprotein of Human papillomavirus type 18 that mediates binding to the PDZ7 and PDZ10 domains of rat Mupp1 (Mpdz)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)