Instance ID11529
Regular Expression[ST]x[VL]$
Motif InstanceTQV
Bait Uniprot AccessionP06463
Bait Uniprot IdentifierVE6_HPV18
Bait Gene NameE6
Bait OrganismHuman papillomavirus type 18
Sequence Position156-158
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Sequence based prediction; Mutational analysis
Interaction ID21529
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17166906, 15492812
CommentsPDZ binding motif in E6 oncoprotein of Human papillomavirus type 18 which mediates the binding and degradation of the protein tyrosine phosphatase PTPN3 (PTPH1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)