Instance ID11546
Regular Expression[ST]x[VL]$
Motif InstanceTQV
Bait Uniprot AccessionP06463
Bait Uniprot IdentifierVE6_HPV18
Bait Gene NameE6
Bait OrganismHuman papillomavirus type 18
Sequence Position156-158
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutational analysis
Interaction ID21546
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17287269
CommentsPDZ binding motif in E6 oncoprotein of Human papillomavirus type 18 that binds to PDZ 4 and 5 and mediates the degradation of the tight junction-associated multi-PDZ protein PATJ (INADL)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)