Instance ID11566
Regular Expression[ST]x[VLI]$
Motif InstanceTGL
Bait Uniprot AccessionP19490
Bait Uniprot IdentifierGRIA1_RAT
Bait Gene NameGria1
Bait OrganismRattus norvegicus (Rat)
Sequence Position905-907
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)X-ray crystallography; Mutational analysis; Pull down(GST tag)
Interaction ID21566
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9677374, 12070168, 17069616
CommentsThe C-terminal type I PDZ binding motif in rat Glutamate receptor 1 (GluR1) or Gria1 that mediates its specific interaction with the second PDZ domain of rat Synapse-associated protein 97 (SAP97) or Disks large homolog 1 (Dlg1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)