Instance ID11618
Regular Expression[FY]x[VLI]$
Motif InstanceFLV
Bait Uniprot AccessionQ9Y624
Bait Uniprot IdentifierJAM1_HUMAN
Bait Gene NameF11R
Bait OrganismHomo sapiens (Human)
Sequence Position297-299
Critical ResiduesP2; P3
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutational analysis
Interaction ID21618
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10877843, 11489913
CommentsThe COOH-terminal class II PDZ-domain binding motif of human JAM (F11R) that directly interacts with PDZ3 domain of human Tight junction protein ZO-1 (TJP1) for recruitment of endogenous ZO-1 to cell–cell adhesion sites

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)