Instance ID11658
Regular Expression[YFG][YFHW][WFA]$
Motif InstanceFYA
Bait Uniprot AccessionP18827
Bait Uniprot IdentifierSDC1_HUMAN
Bait Gene NameSDC1
Bait OrganismHomo sapiens (Human)
Sequence Position308-310
Critical ResiduesP2; P3
Motif PTM(s)Phosphorylation at Tyr-P2
Secondary StructureDisordered
Experimental Method(s)Sequence based prediction; NMR; Fluorescence anisotropy binding assay
Interaction ID21658
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20361982
CommentsClass II-type PDZ-binding motif in the C-terminal sequence of human Syndecan-1 that binds to the Tiam1 PDZ domain

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)