Instance ID11673
Regular ExpressionKKRILHC
Motif InstanceKKRILHC
Bait Uniprot AccessionP53004
Bait Uniprot IdentifierBIEA_HUMAN
Bait Gene NameBLVRA
Bait OrganismHomo sapiens (Human)
Sequence Position275-281
Critical ResiduesP7
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutational analysis; Pull down(GST tag); Competition binding assay
Interaction ID21673
Interacting DomainUnknown
Disease Association(s)Goodpasture syndrome (GPS)
Inhibitor(s)Unknown
Reference(s)20177069
CommentsThe human Biliverdin reductase A (BLVRA) D-Box core sequence that interacts with and inhibits Goodpasture antigen-binding protein (COL4A3BP) from interaction with the docking protein(s) required for its translocation to the cell membrane and points of assembly for signaling molecules that include upstream kinases

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)