Instance ID11690
Regular ExpressionWx{2,3}[FW]
Motif InstanceWVQF
Bait Uniprot AccessionQ9NVZ3
Bait Uniprot IdentifierNECP2_HUMAN
Bait Gene NameNECAP2
Bait OrganismHomo sapiens (Human)
Sequence Position260-263
Critical ResiduesP1; P4
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)NMR; Mutational analysis
Interaction ID21690
Interacting DomainAlpha-ear domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15359277
CommentsThe C-terminal WXXF motif of Adaptin ear-binding coat-associated protein 2 (NECAP2) that mediates binding to the alpha-ear domain of AP-2 complex subunit alpha-1 or Alpha1-adaptin

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)