Instance ID11694
Regular ExpressionWx{2,3}[FW]
Motif InstanceWVTF
Bait Uniprot AccessionO43426
Bait Uniprot IdentifierSYNJ1_HUMAN
Bait Gene NameSYNJ1
Bait OrganismHomo sapiens (Human)
Sequence Position1481-1484
Critical ResiduesP1; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Pull down(GST tag)
Interaction ID21694
Interacting DomainAlpha-ear domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)14565955
CommentsAP-2 interaction motif in the non-neuronal 170-kDa long splice isoform of synaptojanin 1, termed SJ170, that mediates binding to the alpha-ear domain of AP-2 complex subunit alpha-1 or Alpha1-adaptin and is likely to promote efficient targeting of the polyphosphatase to the assembling clathrin lattice in non-neuronal cells


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)