Instance ID11701
Regular ExpressionP[KR]RPPxPR
Motif InstancePKRPPPPR
Bait Uniprot AccessionO43426
Bait Uniprot IdentifierSYNJ1_HUMAN
Bait Gene NameSYNJ1
Bait OrganismHomo sapiens (Human)
Sequence Position1105-1112
Critical ResiduesP2; P4; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Phage Display; Peptide Scanning; ELISA; Competition binding assay
Interaction ID21701
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10542231, 9341169
CommentsThe SH3 domain-binding P[KR]RPPxPR motif (1105-1112) in human Synaptojanin-1 that binds the SH3 domain of human Endophilin-1 (SH3GL2)


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)