Instance ID11732
Regular ExpressionPxxPxR
Motif InstancePPVPPR
Bait Uniprot AccessionP22681
Bait Uniprot IdentifierCBL_HUMAN
Bait Gene NameCBL
Bait OrganismHomo sapiens (Human)
Sequence Position494-499
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; Competition binding assay
Interaction ID21732
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7592693, 7791764
CommentsThe SH3 domain-binding PxxPxR motif in human proto-oncogene c-Cbl that binds the SH3 domains of human adapter protein GRB2

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)