Instance ID11734
Regular ExpressionPxxPxR
Motif InstancePPLPER
Bait Uniprot AccessionP35831
Bait Uniprot IdentifierPTN12_MOUSE
Bait Gene NamePtpn12
Bait OrganismMus musculus (Mouse)
Sequence Position675-680
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Ligand Overlay Assay
Interaction ID21734
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9135065
CommentsThe SH3 domain-binding PxxPxR motif 4 (675-680) in murine protein tyrosine phosphatase-PEST (MPTP-PEST) that binds to the SH3 domains of human adapter protein GRB2

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)