Instance ID11735
Regular ExpressionPxxPxR
Motif InstancePPKPSR
Bait Uniprot AccessionP34152
Bait Uniprot IdentifierFAK1_MOUSE
Bait Gene NamePtk2
Bait OrganismMus musculus (Mouse)
Sequence Position750-755
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; Mutational analysis; Pull down(GST tag)
Interaction ID21735
Interacting DomainSH3 domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)11278488
CommentsThe SH3 domain-binding PxxPxR motif (750-755) in mouse Focal adhesion kinase 1 that binds the SH3 domain of Tyrosine-protein kinase transforming oncoprotein v-Src, a gene product of Rous sarcoma virus

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)