Instance ID11738
Regular ExpressionPxxPxR
Motif InstancePKKPPR
Bait Uniprot AccessionP34152
Bait Uniprot IdentifierFAK1_MOUSE
Bait Gene NamePtk2
Bait OrganismMus musculus (Mouse)
Sequence Position911-916
Critical ResiduesP1; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Site-directed mutagenesis; Y2H
Interaction ID21738
Interacting DomainSH3 domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)9038154
CommentsThe SH3 domain-binding PxxPxR motif (911-916) in mouse Focal adhesion kinase 1 that binds the SH3 domain of a v-Crk-associated tyrosine kinase substrate, p130Cas (Breast cancer anti-estrogen resistance protein 1 or Bcar1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)